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轉(zhuǎn)鐵蛋白單克隆抗體

產(chǎn)品貨號：

BN41978M
中文名稱：

轉(zhuǎn)鐵蛋白單克隆抗體
英文名稱：

Mouse anti-Transferrin(1F10) Monoclonal antibody
品牌：

Biorigin

貨號

產(chǎn)品規(guī)格

售價(jià)

備注
BN41978M-50ul

50ul

￥1486.00

交叉反應(yīng)：Human 推薦應(yīng)用：WB,ELISA
BN41978M-100ul

100ul

￥2360.00

交叉反應(yīng)：Human 推薦應(yīng)用：WB,ELISA

產(chǎn)品描述

英文名稱	Transferrin(1F10)
中文名稱	轉(zhuǎn)鐵蛋白單克隆抗體
別名	Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin.
研究領(lǐng)域	腫瘤細(xì)胞生物免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源	Mouse
克隆類型	Monoclonal
克隆號	1F10
交叉反應(yīng)	Human,
產(chǎn)品應(yīng)用	WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	77kDa
細(xì)胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	Full length native Transferrin protein purified from human plasma:
亞型	IgG
純化方法	affinity purified by Protein A
儲(chǔ) 存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產(chǎn)品介紹	This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009]. Function: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. Subunit: Monomer. Subcellular Location: Secreted. Tissue Specificity: Expressed by the liver and secreted in plasma. DISEASE: Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia. Similarity: Belongs to the transferrin family. Contains 2 transferrin-like domains. SWISS: P02787 Gene ID: 7018 Database links: Entrez Gene: 7018 Human Entrez Gene: 22041 Mouse Entrez Gene: 24825 Rat Omim: 190000 Human SwissProt: P02787 Human SwissProt: Q921I1 Mouse SwissProt: P12346 Rat Unigene: 518267 Human Unigene: 37214 Mouse Unigene: 91296 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.