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P物質抗體

產品貨號：

BN41477R
中文名稱：

P物質抗體
英文名稱：

Rabbit anti-Substance P Polyclonal antibody
品牌：

Biorigin

貨號

產品規(guī)格

售價

備注
BN41477R-50ul

50ul

￥1486.00

交叉反應：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41477R-100ul

100ul

￥2360.00

交叉反應：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA
BN41477R-200ul

200ul

￥3490.00

交叉反應：Human,Mouse,Rat,GuineaPig(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推薦應用：IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

產品描述

英文名稱	Substance P
中文名稱	P物質抗體
別名	Hs.2563; Neurokinin 1; Neurokinin 2; Neurokinin A; Neurokinin alpha; Neuromedin L; Neuropeptide gamma; NKA; NKNA; PPT; Protachykinin 1 precursor; Substance K; Substance P; TAC1; TAC2; Tachykinin 1; Tachykinin 2; Tachykinin precursor 1; Tachykinin1; TACI; TKN1_HUMAN.

研究領域	神經生物學新陳代謝
抗體來源	Rabbit
克隆類型	Polyclonal
交叉反應	Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產品應用	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	1.4/13kDa
細胞定位	分泌型蛋白
性狀	Liquid
濃度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human Substance P(RPKPQQFFGLM):58-68/129
亞型	IgG
純化方法	affinity purified by Protein A
儲存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
產品介紹	This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Subcellular Location: Secreted. Similarity: Belongs to the tachykinin family. SWISS: P20366 Gene ID: 6863 Database links: Entrez Gene: 6863 Human Entrez Gene: 21333 Mouse Entrez Gene: 24806 Rat Omim: 162320 Human SwissProt: P20366 Human SwissProt: P41539 Mouse SwissProt: P06767 Rat Unigene: 2563 Human UniProtKB/Swiss-Prot: P20366.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. P物質（Substance P）是腦組織及消化道中發(fā)現(xiàn)的一種神經遞質肽。由130個氨基酸殘基組成，胃腸道中肌肉收縮的有力促進劑，亦為強血管擴張劑。 SP是一種腦腸肽，亦是最早發(fā)現(xiàn)的一種神經肽，屬于速激肽家族成員，它廣泛分布于中樞及外周神經系統(tǒng)，作為一種神經遞質或調質參與疼痛、免疫、心血管等多種生理功能的調節(jié)。SP與其它的遞質或調質類似，能作用于多種類型的受體，速激肽家族有NK1、NK2、NK3三種受體，都能與SP結合，其中NK1與SP的結合能力最強而被稱為SP受體。